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Chemical Structure : PRN473
Catalog No.: PC-38012Not For Human Use, Lab Use Only.
PRN473 (Atuzabrutinib, SAR 444727, PRN-473) is a potent, selective, covalent reversible BTK inhibitor.
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PRN473 (Atuzabrutinib, SAR 444727, PRN-473) is a potent, selective, covalent reversible BTK inhibitor.
PRN473 demonstrates in vivo efficacy in rodent arthritis models, and clinical efficacy in canine pemphigus foliaceus. PRN473 has completed phase 1 trials as a topical agent.
| M.Wt | 539.615 | |
| Formula | C30H30FN7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Herter JM, et al. Br J Pharmacol. 2018;175(3):429-439.
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