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PROTAC-VHL-ligand

Chemical Structure : PROTAC-VHL-ligand

CAS No.: 1448297-52-6

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PROTAC-VHL-ligand

Catalog No.: PC-62218Not For Human Use, Lab Use Only.

PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.

Physicochemical Properties

M.Wt 430.567
Formula C22H30N4O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO
Chemical Name/SMILES

L-Prolinamide,3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-,(4R)-

References

1. Bondeson DP, et al. Nat Chem Biol. 2015 Aug;11(8):611-7.

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