PROTAC AGB1

Chemical Structure : PROTAC AGB1

Catalog No.: PC-23037Not For Human Use, Lab Use Only.

PROTAC AGB1 is a potent, fast, and selective degrader of BromoTagged proteins with DC50 of <15 nM.

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Biological Activity

PROTAC AGB1 is a potent, fast, and selective degrader of BromoTagged proteins with DC50 of <15 nM.

M.Wt	1031.68
Formula	C51H63ClN8O9S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-13-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecyl (R)-2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoate

1. Adam G Bond, et al. J Med Chem. 2021 Oct 28;64(20):15477-15502.

2. Tejwani V, et al. Sci Rep. 2024 Sep 6;14(1):20824.