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PS1

Chemical Structure : PS1

CAS No.: 1207994-72-6

PS1 (IAP inhibitor PS1)

Catalog No.: PC-62352Not For Human Use, Lab Use Only.

PS1 is a potent inhibitor of IAP family with IC50 of 36/96/33 nM for c-IAP1/c-IAP2/XIAP respectively..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PS1 is a potent inhibitor of IAP family with IC50 of 36/96/33 nM for c-IAP1/c-IAP2/XIAP respectively.

    Physicochemical Properties

    M.Wt 542.095
    Formula C27H32ClN5O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-N-((S)-2-((S)-2-(4-(2-chlorophenyl)thiazolo[4,5-c]pyridin-2-yl)pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)-2-(methylamino)propanamide

    References

    1. Ndubaku C, et al. ACS Chem Biol. 2009 Jul 17;4(7):557-66.

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