Catalog No.: PC-63500Not For Human Use, Lab Use Only.
PS10 (PDK inhibitor PS10) is a novel potent and highly selective pyruvate dehydrogenase kinase (PDK) inhibitor with IC50 values of 0.8 μM, 0.76 μM, 2.1 μM and 21.3 μM for PDK2, PDK4, PDK1, and PDK3, respectively.
PS10 (PDK inhibitor PS10) is a novel potent and highly selective pyruvate dehydrogenase kinase (PDK) inhibitor with IC50 values of 0.8 μM, 0.76 μM, 2.1 μM and 21.3 μM for PDK2, PDK4, PDK1, and PDK3, respectively.
PS10 improved glucose tolerance, stimulates myocardial carbohydrate oxidation in diet-induced obesity.
PS10 is a more suitable PDK inhibitor for treatment of diabetic cardiomyopathy.
