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PS10

Chemical Structure : PS10

CAS No.: 1564265-82-2

PS10 (PDK inhibitor PS10)

Catalog No.: PC-63500Not For Human Use, Lab Use Only.

PS10 (PDK inhibitor PS10) is a novel potent and highly selective pyruvate dehydrogenase kinase (PDK) inhibitor.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PS10 (PDK inhibitor PS10) is a novel potent and highly selective pyruvate dehydrogenase kinase (PDK) inhibitor; improved glucose tolerance, stimulates myocardial carbohydrate oxidation in diet-induced obesity; PS10 is a more suitable PDK inhibitor for treatment of diabetic cardiomyopathy.

Physicochemical Properties

M.Wt 323.319
Formula C14H13NO6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[(2,4-dihydroxyphenyl)sulfonyl] isoindoline-4,6-diol

References

1. Wu CY, et al. J Biol Chem. 2018 May 8. pii: jbc.RA118.002838.

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