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PST-1

Chemical Structure : PST-1

CAS No.: 1801769-39-0

PST-1 (Microtubule photoswitchable inhibitor)

Catalog No.: PC-62674Not For Human Use, Lab Use Only.

PST-1 is a photoswitchable inhibitor of microtubule with EC50 of 0.5 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines, 100-fold more cytotoxic than in the dark.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PST-1 is a photoswitchable inhibitor of microtubule with EC50 of 0.5 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines, 100-fold more cytotoxic than in the dark.

    Physicochemical Properties

    M.Wt 318.329
    Formula C16H18N2O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (Z)-2-methoxy-5-((3,4,5-trimethoxyphenyl)diazenyl)phenol

    References

    1. Borowiak M, et al. Cell. 2015 Jul 16;162(2):403-11.

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