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Chemical Structure : PST-1P
Catalog No.: PC-62673Not For Human Use, Lab Use Only.
PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines.
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PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines.
PST-1P is100-fold more cytotoxic than in the dark.
PST-1P induces mitotic arrest and cell death in a light-dependent manner, and controls mitosis and the microtubule cytoskeleton in mammalian tissue in vivo.
PST-1P is the highly water-soluble prodrug of PST-1.
| M.Wt | 398.308 | |
| Formula | C16H19N2O8P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Borowiak M, et al. Cell. 2015 Jul 16;162(2):403-11.
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