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PTA-1

Chemical Structure : PTA-1

CAS No.: 1185699-58-4

PTA-1

Catalog No.: PC-22831Not For Human Use, Lab Use Only.

PTA-1 is a potent anticancer compound, disturbs microtubule organization and inhibits tubulin polymerization, shows cytotoxicity to various cancer cells (MCF-7, CC50=0.23 uM), induces apoptosis and cell cycle arrest.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PTA-1 is a potent anticancer compound, disturbs microtubule organization and inhibits tubulin polymerization, shows cytotoxicity to various cancer cells (MCF-7, CC50=0.23 uM), induces apoptosis and cell cycle arrest.

Physicochemical Properties

M.Wt 380.33
Formula C16H15F3N6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-{4-[4-methoxy-3-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl}-N-(2-methyl-2H-1,2,3-triazol-4-yl) acetamide

References

1. Borrego EA, et al. Cells. 2024 Jul 20;13(14):1225.

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