PUC-55

Chemical Structure : PUC-55

Catalog No.: PC-24221Not For Human Use, Lab Use Only.

PUC-10 is a selective 5-HT6 receptor antagonist high binding affinity (Ki=37.5 nM), induces autophagy in the neuroblastoma SH-SY5Y cell line by inhibiting the mTOR pathway.

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Biological Activity

PUC-10 is a selective 5-HT6 receptor antagonist high binding affinity (Ki=37.5 nM), induces autophagy in the neuroblastoma SH-SY5Y cell line by inhibiting the mTOR pathway.

Physicochemical Properties

M.Wt	542.65
Formula	C30H30N4O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(1-(naphthalen-1-ylsulfonyl)-1H-indazol-3-yl)ethan-1-ol

References

1. Alcaíno JM, et al. Sci Rep. 2025 Mar 11;15(1):8380. doi: 10.1038/s41598-025-92755-6.

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PUC-55

Biological Activity

Physicochemical Properties

References

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