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Paclitaxel

Chemical Structure : Paclitaxel

CAS No.: 33069-62-4

Paclitaxel

Catalog No.: PC-25975Not For Human Use, Lab Use Only.

Paclitaxel is a naturally occurring antineoplastic agent and tubulin polymerization stabilizer, induces both mitotic arrest and apoptotic cell death, also induces autophagy.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Paclitaxel is a naturally occurring antineoplastic agent and tubulin polymerization stabilizer, induces both mitotic arrest and apoptotic cell death, also induces autophagy.

Physicochemical Properties

M.Wt 853.91
Formula C47H51NO14
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b-diyl diacetate

References

1. Choi YH, et al. Oncol Rep. 2012 Dec;28(6):2163-9.

2. Dziadyk JM, et al. Anticancer Res. 2004 Jan-Feb;24(1):27-36.

3. Pan Z, et al. Biochem Biophys Res Commun. 2013 Feb 13. pii: S0006-291X(13)00259-3.

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