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Chemical Structure : Pactamycin
Catalog No.: PC-62849Not For Human Use, Lab Use Only.
Pactamycin (NSC 52947) is a potent protein synthesis inhibitor, inhibits protein synthesis at the translocation step on the 70S ribosome, has activity against Gram-positive and Gram-negative bacteria, and broad antitumor, antiviral, and antiplasmodial activity.
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Pactamycin (NSC 52947) is a potent protein synthesis inhibitor, inhibits protein synthesis at the translocation step on the 70S ribosome, has activity against Gram-positive and Gram-negative bacteria, and broad antitumor, antiviral, and antiplasmodial activity.
| M.Wt | 558.62 | |
| Formula | C28H38N4O8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bhuyan BK. Biochem Pharmacol. 1967 Aug;16(8):1411-20.
2. Suzuki H, et al. Proc Natl Acad Sci U S A. 1974 Oct;71(10):4259-63.
3. Kappen LS, et al. Biochemistry. 1976 Feb 24;15(4):811-8.
4. Hanessian S, et al. Bioorg Med Chem. 2013 Apr 1;21(7):1775-86.
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