Palonosetron hydrochloride | 5-HT3 antagonist

Chemical Structure : Palonosetron hydrochloride

CAS No.: 135729-62-3

Palonosetron hydrochloride (RS 25259-197)

Catalog No.: PC-24876Not For Human Use, Lab Use Only.

Palonosetron (RS 25259-197) is a potent, selective 5-HT3 receptor antagonist with pKi value of 10.4, >10,000-fold selective over 5-HT1A/1D/2A/2C receptors.

Packing	Price	Stock
50 mg	$48	In stock
100 mg	$78	In stock
250 mg	$128	In stock
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Biological Activity

Palonosetron (RS 25259-197) is a potent, selective 5-HT3 receptor antagonist with pKi value of 10.4, >10,000-fold selective over 5-HT1A/1D/2A/2C receptors.

Physicochemical Properties

M.Wt	332.87
Formula	C19H25ClN2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride

References

1. Clark RD, et al. J Med Chem. 1993 Sep 3;36(18):2645-57.

2. Wong EH, et al. Br J Pharmacol. 1995 Feb;114(4):851-9.

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Palonosetron hydrochloride (RS 25259-197)

Biological Activity

Physicochemical Properties

References

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