Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Urotensin Receptor-Palosuran
Palosuran

Chemical Structure : Palosuran

CAS No.: 540769-28-6

Palosuran (ACT058362, ACT 058362, ACT-058362)

Catalog No.: PC-42692Not For Human Use, Lab Use Only.

Palosuran (ACT-058362) is a potent and specific antagonist of human Urotensin (UT) receptor.

Packing Price Stock Quantity
5 mg $68 In stock
10 mg $98 In stock
25 mg $158 In stock
50 mg $248 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Palosuran (ACT-058362) is a potent and specific antagonist of human Urotensin (UT) receptor.
Palosuran (ACT-058362) inhibits 125I-U-II binding to human UT receptors in membrane preparations from CHO cells carrying the human UT receptors with IC50 of 3.6 nM.
Palosuran (ACT-058362) prevents the development of acute renal failure and the histological consequences of ischemia in rats.

Physicochemical Properties

M.Wt 418.5313
Formula C25H30N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

Urea, N-[2-[4-hydroxy-4-(phenylmethyl)-1-piperidinyl]ethyl]-N'-(2-methyl-4-quinolinyl)-

References

1. Clozel M, et al. J Pharmacol Exp Ther. 2004 Oct;311(1):204-12.

2. Clozel M, et al. J Pharmacol Exp Ther. 2006 Mar;316(3):1115-21.

3. Behm DJ, et al. Br J Pharmacol. 2008 Oct;155(3):374-86.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: