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Chemical Structure : Palosuran
CAS No.: 540769-28-6
Catalog No.: PC-42692Not For Human Use, Lab Use Only.
Palosuran (ACT-058362) is a potent and specific antagonist of human Urotensin (UT) receptor.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $68 | In stock | |
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | Get quote |
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Palosuran (ACT-058362) is a potent and specific antagonist of human Urotensin (UT) receptor.
Palosuran (ACT-058362) inhibits 125I-U-II binding to human UT receptors in membrane preparations from CHO cells carrying the human UT receptors with IC50 of 3.6 nM.
Palosuran (ACT-058362) prevents the development of acute renal failure and the histological consequences of ischemia in rats.
| M.Wt | 418.5313 | |
| Formula | C25H30N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 30 mg/mL |
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| Chemical Name/SMILES |
Urea, N-[2-[4-hydroxy-4-(phenylmethyl)-1-piperidinyl]ethyl]-N'-(2-methyl-4-quinolinyl)- |
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1. Clozel M, et al. J Pharmacol Exp Ther. 2004 Oct;311(1):204-12.
2. Clozel M, et al. J Pharmacol Exp Ther. 2006 Mar;316(3):1115-21.
3. Behm DJ, et al. Br J Pharmacol. 2008 Oct;155(3):374-86.
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