Pantoprazole sodium (SKF-96022 sodium) is a proton pump inhibitor that inhibits gastric acid secretion.
Pantoprazole sodium works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.
Pantoprazole sodium inhibits autophagy and increases the toxicity of docetaxel in vitro and in vivo.
Physicochemical Properties
M.Wt
405.3516
Formula
C16H14F2N3NaO4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
H2O: ≥ 35 mg/mL
Chemical Name/SMILES
1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
References
1. Tan Q, et al. Br J Cancer. 2015 Mar 3;112(5):832-40.
2. Feng S, et al. Oncol Rep. 2016 Dec;36(6):3207-3214.
3. Zeng X, et al. Oncotarget. 2016 Apr 19;7(16):22460-73.
