Chemical Structure : Paroxetine
CAS No.: 61869-08-7
Catalog No.: PC-23760Not For Human Use, Lab Use Only.
Paroxetine hydrochloride is an oral, selective serotonin reuptake inhibitor (SSRI), also is a direct, selective inhibitor of G protein-coupled receptor kinase 2 (GRK2) with pIC50 of 5.6.
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Paroxetine hydrochloride is an oral, selective serotonin reuptake inhibitor (SSRI), also is a direct, selective inhibitor of G protein-coupled receptor kinase 2 (GRK2) with pIC50 of 5.6.
Paroxetine also is a weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity,
Paroxetine induces autophagy dependent-NLRP3-inflammasome inhibition in Major depressive disorder.
M.Wt | 329.37 | |
Formula | C19H20FNO3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine |
1. Thal DM, et al. ACS Chem Biol. 2012 Nov 16;7(11):1830-9.
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