Chemical Structure : Paroxetine hydrochloride hemihydrate
CAS No.:
110429-35-1
Paroxetine hydrochloride hemihydrate
(BRL29060 hydrochloride hemihydrate;BRL29060A hemihydrate)
Catalog No. : PC-46650Not For Human Use, Lab Use Only.
An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4665001
Biological Activity
An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class; also shows to be a selective inhibitor of GRK2 activity both in vitro and in living cells; induce autophagy dependent-NLRP3-inflammasome inhibition in Major depressive disorder.
Depression
Approved
Physicochemical Properties
M.Wt
374.83
Formula
C19H22ClFNO3.5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:2:1), (3S,4R)-
References
1. Thal DM, et al. ACS Chem Biol. 2012 Nov 16;7(11):1830-9.
2. Gassen NC, et al. Autophagy. 2015;11(3):578-80.
3. Alcocer-Gómez E, et al. Pharmacol Res. 2017 Jul;121:114-121.
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