Chemical Structure : Paroxetine hydrochloride hemihydrate
CAS No.: 110429-35-1
Catalog No.: PC-46650Not For Human Use, Lab Use Only.
An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
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An antidepressant of the selective serotonin reuptake inhibitor (SSRI) class; also shows to be a selective inhibitor of GRK2 activity both in vitro and in living cells; induce autophagy dependent-NLRP3-inflammasome inhibition in Major depressive disorder.
Depression
Approved
M.Wt | 374.83 | |
Formula | C19H22ClFNO3.5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride, hydrate (2:2:1), (3S,4R)- |
1. Thal DM, et al. ACS Chem Biol. 2012 Nov 16;7(11):1830-9.
2. Gassen NC, et al. Autophagy. 2015;11(3):578-80.
3. Alcocer-Gómez E, et al. Pharmacol Res. 2017 Jul;121:114-121.
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