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Chemical Structure : Pasireotide L-aspartate salt
Catalog No.: PC-46000Not For Human Use, Lab Use Only.
Pasireotide (SOM230) L-aspartate is a potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (pKi=8.2/9.0/9.1/<7.0/9.9 for sst1/2/3/4/5, respectively).
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Pasireotide (SOM230) L-aspartate is a potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (pKi=8.2/9.0/9.1/<7.0/9.9 for sst1/2/3/4/5, respectively).
Pasireotide effectively inhibits GHRH-induced growth hormone release in primary cultures of rat pituitary cells with IC50 of 0.4 nM, also potently suppresses GH secretion in rats.
| M.Wt | 1180.309 | |
| Formula | C62H73N11O13 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lewis I, et al. J Med Chem. 2003 Jun 5;46(12):2334-44.
2. Bruns C, et al. Eur J Endocrinol. 2002 May;146(5):707-16.
3. Hofland LJ, et al. Eur J Endocrinol. 2005 Apr;152(4):645-54.
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