Pasireotide acetate | SSTR agonist | Probechem Biochemicals

Chemical Structure : Pasireotide acetate

CAS No.: 396091-76-2

Pasireotide acetate (SOM230 acetate, SOM-230 acetate)

Catalog No.: PC-22363Not For Human Use, Lab Use Only.

Packing	Price	Stock
5 mg	$258	In stock
10 mg	$428	In stock
25 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Pasireotide (SOM230) acetate is a potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (pKi=8.2/9.0/9.1/<7.0/9.9 for sst1/2/3/4/5, respectively).
Pasireotide (SOM230) effectively inhibits GHRH-induced growth hormone release in primary cultures of rat pituitary cells with IC50 of 0.4 nM.
Pasireotide (SOM230) also potently suppresses GH secretion in rats.

Physicochemical Properties

M.Wt	1107.28
Formula	C60H70N10O11
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	acetic acid;[(3S,6S,9S,12R,15S,18S,20R)-9-(4-aminobutyl)-3-benzyl-12-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-15-phenyl-6-[(4-phenylmethoxyphenyl)methyl]-1,4,7,10,13,16-hexazabicyclo[16.3.0]henicosan-20-yl] N-(2-aminoethyl)carbamate

References

1. Lewis I, et al. J Med Chem. 2003 Jun 5;46(12):2334-44.

2. Bruns C, et al. Eur J Endocrinol. 2002 May;146(5):707-16.

3. Hofland LJ, et al. Eur J Endocrinol. 2005 Apr;152(4):645-54.

Pasireotide acetate (SOM230 acetate, SOM-230 acetate)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.