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Petrelintide

Chemical Structure : Petrelintide

CAS No.: 2766385-23-1

Petrelintide (ZP8396)

Catalog No.: PC-27450Not For Human Use, Lab Use Only.

Petrelintide (ZP8396) is a potent, stable, long-acting analogue of human amylin, has potent agonistic effects on amylin receptors (AMY1 and AMY3) and the calcitonin receptor relative to human amylin and human calcitonin respectively, induces dose‐dependent reductions in food intake and body weight.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Petrelintide (ZP8396) is a potent, stable, long-acting analogue of human amylin, has potent agonistic effects on amylin receptors (AMY1 and AMY3) and the calcitonin receptor relative to human amylin and human calcitonin respectively, induces dose‐dependent reductions in food intake and body weight.

Physicochemical Properties

M.Wt 4191.69
Formula C185H305N49O61
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

{γGlu-arachidate}-Arg-Asp-Gly-Thr-Ala-Thr-Lys-Ala-Thr-Glu-Arg-Leu-Ala-{homoGlu}-Phe-Leu-Gln-Arg-Ser-Ser-Phe-{Sar}-Ala{NMeIle}-Leu-Ser-Ser-Thr-Glu-Val-Gly-Ser-Asn-Thr-{Hyp}-NH2 (Lactm bridge:Asp3-Lys8)

References

1. Fischer Munch H, et al. J Med Chem. 2025 Nov 27;68(22):23925-23940.

2. Brændholt Olsen M, et al. Diabetes Obes Metab. 2026 Jul;28(7):5915-5925.

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