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Petrelintide acetate

Chemical Structure : Petrelintide acetate

CAS No.:

Petrelintide acetate (ZP8396 acetate)

Catalog No.: PC-27451Not For Human Use, Lab Use Only.

Petrelintide acetate (ZP8396 acetate) is a potent, stable, long-acting analogue of human amylin, has potent agonistic effects on amylin receptors (AMY1 and AMY3) and the calcitonin receptor relative to human amylin and human calcitonin respectively, induces dose‐dependent reductions in food intake and body weight.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Petrelintide acetate (ZP8396 acetate) is a potent, stable, long-acting analogue of human amylin, has potent agonistic effects on amylin receptors (AMY1 and AMY3) and the calcitonin receptor relative to human amylin and human calcitonin respectively, induces dose‐dependent reductions in food intake and body weight.

Physicochemical Properties

M.Wt 4191.69 (free base)
Formula C185H305N49O61.xC2H4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

{γGlu-arachidate}-Arg-Asp-Gly-Thr-Ala-Thr-Lys-Ala-Thr-Glu-Arg-Leu-Ala-{homoGlu}-Phe-Leu-Gln-Arg-Ser-Ser-Phe-{Sar}-Ala{NMeIle}-Leu-Ser-Ser-Thr-Glu-Val-Gly-Ser-Asn-Thr-{Hyp}-NH2 (Lactm bridge:Asp3-Lys8) acetate salt

References

1. Fischer Munch H, et al. J Med Chem. 2025 Nov 27;68(22):23925-23940.

2. Brændholt Olsen M, et al. Diabetes Obes Metab. 2026 Jul;28(7):5915-5925.

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