Catalog No.: PC-61269Not For Human Use, Lab Use Only.
Pexacerfont (BMS562086, DPC-A69448) is a potent, selective and orally active CRF1 receptor antagonist with IC50 of 6.1 nM, >1,000-fold selectivity over CRF-binding protein and biogenic amine receptors.
Pexacerfont (BMS562086, DPC-A69448) is a potent, selective and orally active CRF1 receptor antagonist with IC50 of 6.1 nM, >1,000-fold selectivity over CRF-binding protein and biogenic amine receptors.
Pexacerfont (BMS562086, DPC-A69448) demonstrates oral effectivity in rat models of anxiety, possesses good pharmacokinetic profile in vivo.
