Chemical Structure : Pexiganan acetate
CAS No.:
172820-23-4
Pexiganan acetate
Catalog No.: PC-27794Not For Human Use, Lab Use Only.
Pexiganan acetate (MSI-78) is an analog of magainin and orally active antimicrobial peptide with broad-spectrum bactericidal activity, disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis, has MIC90 of ≤ 32 ug/mL for clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
Pexiganan acetate (MSI-78) is an analog of magainin and orally active antimicrobial peptide with broad-spectrum bactericidal activity, disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis, has MIC90 of ≤ 32 ug/mL for clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria.
Physicochemical Properties
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M.Wt
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Formula
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C122H210N32O22.xC2H4O2
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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L-Lysinamide, glycyl-L-isoleucylglycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-phenylalanylglycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-lysyl-L-isoleucyl-L-leucyl-L-lysyl-, acetate (1:?)
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References
1. Ge Y, et al. Antimicrob Agents Chemother. 1999 Apr;43(4):782-8.
2. Fuchs PC, et al. Antimicrob Agents Chemother. 1998 May;42(5):1213-6.
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