Pezulepistat

Chemical Structure : Pezulepistat

Catalog No.: PC-25078Not For Human Use, Lab Use Only.

Pezulepistat (Compound II) is a potent, selective inhibitor of bacterial type 1 signal peptidase LepB, shows serum MIC value of 0.5 μM against E. coli 25922, exhibits broad spectrum antibiotic activity.

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Biological Activity

Physicochemical Properties

M.Wt	1008.12
Formula	C46H61N11O13S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	OC1=C2C3=C(OC[C@@H](CN)O)C=CC(=C3)C[C@@H](C(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N(C([C@@H](NC(=O)C=4C(C)=NC(=NC4N)C5=CC=C(C(C)(C)C)C=C5)CNS(N)(=O)=O)=O)C)C(=C2)C=C1OC[C@@H](CN)O

References

1. Patent WO2020243155 A1.

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Pezulepistat

Biological Activity

Physicochemical Properties

References

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