Chemical Structure : Phenamil methanesulfonate
CAS No.: 1161-94-0
Catalog No.: PC-23761Not For Human Use, Lab Use Only.
Phenamil methanesulfonate is a potent, reversible epithelial sodium channel (ENaC) blocker with IC50 of 400 nM, is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca2+ transport with IC50 of 140 nM in Ca2+ uptake assay.
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Phenamil methanesulfonate is a potent, reversible epithelial sodium channel (ENaC) blocker with IC50 of 400 nM, is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca2+ transport with IC50 of 140 nM in Ca2+ uptake assay.
M.Wt | 401.83 | |
Formula | C13H16ClN7O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3,5-Diamino-6-chloro-N-(N-phenylcarbamimidoyl)pyrazine-2-carboxamide methanesulfonate |
1. Xiao-Qing Dai , et al. Mol Pharmacol. . 2007 Dec;72(6):1576-85.
2. Andrew J Hirsh, et al. J Med Chem. 2006 Jul 13;49(14):4098-115.
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