Phenamil methanesulfonate

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Chemical Structure : Phenamil methanesulfonate

CAS No.: 1161-94-0

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Catalog No.: PC-23761Not For Human Use, Lab Use Only.

Phenamil methanesulfonate is a potent, reversible epithelial sodium channel (ENaC) blocker with IC50 of 400 nM, is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca2+ transport with IC50 of 140 nM in Ca2+ uptake assay.

Packing	Price	Stock
5 mg	$148	In stock
10 mg	$218	In stock
25 mg	$378	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	401.83
Formula	C13H16ClN7O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3,5-Diamino-6-chloro-N-(N-phenylcarbamimidoyl)pyrazine-2-carboxamide methanesulfonate

References

1. Xiao-Qing Dai , et al. Mol Pharmacol. . 2007 Dec;72(6):1576-85.

2. Andrew J Hirsh, et al. J Med Chem. 2006 Jul 13;49(14):4098-115.

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