Catalog No.: PC-60777Not For Human Use, Lab Use Only.
Phortress (NSC710305) is the L-lysylamide prodrug of 5F-203 (NSC703786), a potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway.
Phortress (NSC710305) is the L-lysylamide prodrug of 5F-203 (NSC703786), a potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway.
Phortress (NSC710305) causes MCF-7 sensitive cells to arrest in G(1) and S phase, and induces DNA adduct formation, in contrast to AhR-deficient AH(R100) variant MCF-7 cells.
Phortress (NSC710305) induces CYP1A1 and CYP1B1 transcription; demonstrats antitumor activity in vivo.
