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Chemical Structure : Piclamilast
CAS No.: 144035-83-6
Catalog No.: PC-63089Not For Human Use, Lab Use Only.
Piclamilast (RP-73401) is a potent and highly selective PDE4 inhibitor with IC50 of 1.2 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $138 | In stock | |
| 10 mg | $218 | In stock | |
| 25 mg | $388 | In stock | |
| 50 mg | $598 | In stock | |
| 100 mg | Get quote |
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Piclamilast (RP-73401) is a potent and highly selective PDE4 inhibitor with IC50 of 1.2 nM.
Piclamilast displays >19,000-fold selectivity for PDE4 compared to other PDE isoenzymes.
Piclamilast shows anti-inflammatory and bronchodilator properties in guinea-pig and rat models of bronchoconstriction and allergic inflammation.
| M.Wt | 381.253 | |
| Formula | C18H18Cl2N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-(Cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-benzamide |
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1. Ashton MJ, et al. J Med Chem. 1994 May 27;37(11):1696-703.
2. Raeburn D, et al. Br J Pharmacol. 1994 Dec;113(4):1423-31.
3. Souness JE, et al. Br J Pharmacol. 1995 May;115(1):39-46.
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