Catalog No.: PC-25775Not For Human Use, Lab Use Only.
Pinokalant (LOE908, LOE-908) is an inhibitor of receptor-operated Ca(2+) channels (ROCCs) and non-selective cation channel inhibitor, inhibits store-operated Ca2+ entry (SOCE) induced by direct depletion of Ca2+ stores with 100 nM thapsigargin or 100 nM ionomycin with EC50 of 2 uM and 4 uM, respectively.
Pinokalant (LOE908, LOE-908) is an inhibitor of receptor-operated Ca(2+) channels (ROCCs) and non-selective cation channel inhibitor, inhibits store-operated Ca2+ entry (SOCE) induced by direct depletion of Ca2+ stores with 100 nM thapsigargin or 100 nM ionomycin with EC50 of 2 uM and 4 uM, respectively. Pinokalant (LOE908, LOE-908) does not affect thapsigargin- or ionomycin-induced Ca2+ release from intracellular stores. Pinokalant (LOE908, LOE-908) reversibly suppressed thapsigargin- as well as ionomycin-induced whole-cell membrane currents.
