Chemical Structure : Pitolisant hydrochloride
CAS No.:
903576-44-3
Pitolisant hydrochloride
(Ciproxidine, BF2649, BF-2649)
Catalog No. : PC-42911Not For Human Use, Lab Use Only.
Pitolisant hydrochloride (Ciproxidine, BF2649) is a potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4291101
Biological Activity
Pitolisant hydrochloride (Ciproxidine, BF2649) is a potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM.
Physicochemical Properties
M.Wt
332.3084
Formula
C17H27Cl2NO
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 43 mg/mL
Chemical Name/SMILES
Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-, hydrochloride (1:1)
References
1. Ligneau X, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):365-75.
2. Dudek M, et al. Metab Brain Dis. 2016 Oct;31(5):1023-9.
3. Ligneau X, et al. Biochem Pharmacol. 2007 Apr 15;73(8):1215-24.
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