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Chemical Structure : Pixantrone
CAS No.: 144675-97-8
Catalog No.: PC-22736Not For Human Use, Lab Use Only.
Pixantrone (BBR2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator with anti-tumor activity, also is a direct mini-chromosome maintenance protein 2 (MCM2) inhibitor, induces cell cycle arrest and apoptosis in ovarian cancer cells via targeting MCM2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | Get quote |
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Pixantrone (BBR2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator with anti-tumor activity, also is a direct mini-chromosome maintenance protein 2 (MCM2) inhibitor, induces cell cycle arrest and apoptosis in ovarian cancer cells via targeting MCM2.
| M.Wt | 557.52 | |
| Formula | C25H27N5O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
6,9-Bis((2-aminoethyl)amino)benzo[g]isoquinoline-5,10-dione dimaleate |
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1. Chen Q, et al. Eur J Pharmacol. 2024 Jul 18:176835.et al.
2. Beeharry N, et al. Cancer Biol Ther. 2015;16(9):1397-406.
3. Hasinoff BB, et al. J Pharmacol Exp Ther. 2016 Feb;356(2):397-409.
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