Pixavir marboxilo (TG-1000) | Cap-dependent endonuclease inhibitor

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Chemical Structure : Pixavir marboxilo

CAS No.: 2365473-17-0

Pixavir marboxilo (TG-1000, TG1000)

Catalog No.: PC-49376Not For Human Use, Lab Use Only.

Pixavir marboxilo (TG-1000) is a small molecule Cap-dependent endonuclease inhibitor with potential anti-influenza activity.

Packing	Price	Stock
2 mg	$328	In stock
5 mg	$528	In stock
10 mg	$898	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pixavir marboxilo (TG-1000) is a small molecule Cap-dependent endonuclease inhibitor, blocks the replication and transmission of the influenza virus via a cap-snatching mechanism, shows activity against influenza-A, influenza-B, and Tamiflu-resistant viruses.

Physicochemical Properties

M.Wt	540.538
Formula	C27H22F2N2O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	[[1'-[(11S)-7,8-Difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-1',2',4',6'-tetrahydro-4',6'-dioxospiro[cyclopropane-1,3'-[3H]pyrido[1,2-b]pyridazin]-5'-yl]oxy]methyl methyl carbonate

References

1. Patent WO2019144089 A1.

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Pixavir marboxilo (TG-1000, TG1000)

Biological Activity

Physicochemical Properties

References

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