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Chemical Structure : Plitidepsin
CAS No.: 137219-37-5
Catalog No.: PC-21728Not For Human Use, Lab Use Only.
Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 with KD value of 80 nM, shows antiviral activity against SARS-CoV-2 with IC90 of 0.88 nM.
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|---|---|---|---|
| 1 mg | $348 | In stock | |
| 5 mg | $528 | In stock | |
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Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 with KD value of 80 nM, shows antiviral activity against SARS-CoV-2 with IC90 of 0.88 nM.
| M.Wt | 1110.36 | |
| Formula | C57H87N7O15 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-N-((R)-1-(((3S,6R,7S,10R,11S,15S,17S,20S,25aS)-10-((S)-sec-butyl)-11-hydroxy-20-isobutyl-15-isopropyl-3-(4-methoxybenzyl)-2,6,17-trimethyl-1,4,8,13,16,18,21-heptaoxodocosahydro-15H-pyrrolo[2,1-f][1,15]dioxa[4,7,10,20]tetraazacyclotricosin-7-yl)amino)-4-methyl-1-oxopentan-2-yl)-N-methyl-1-(2-oxopropanoyl)pyrrolidine-2-carboxamide |
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1. Alejandro Losada, et al. Sci Rep. 2016 Oct 7;6:35100.
2. Kris M White, et al. Science. 2021 Feb 26;371(6532):926-931.
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