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Chemical Structure : Polyoxyethylene stearate
CAS No.: 9004-99-3
Catalog No.: PC-42403Not For Human Use, Lab Use Only.
Polyoxyethylene stearate (PS40) is a non-ionic emulsifying agent that can modulate multidrug resistance and enhances antitumor activity of vinblastine sulfate by modulating substrate-stimulated P-gp ATPase activity.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 g | $48 | In stock | |
| 5 g | $88 | In stock | |
| 10 g | Get quote |
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Polyoxyethylene stearate (PS40) is a non-ionic emulsifying agent that can modulate multidrug resistance and enhances antitumor activity of vinblastine sulfate by modulating substrate-stimulated P-gp ATPase activity.
Polyoxyethylene stearate inhibits P-gp mediated efflux in a concentration-dependent manner in Caco-2 cells.
Polyoxyethylene stearate also shows potential inhibitory activitites agasint CYP2C9 and CYP2C19.
| M.Wt | 725.00284 | |
| Formula | (C2H4O)10C18H36O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 49 mg/mL |
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| Chemical Name/SMILES |
Poly(oxy-1,2-ethanediyl), α-(1-oxooctadecyl)-ω-hydroxy- |
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1. Cutler RR, et al. Tubercle. 1987 Sep;68(3):209-20.
2. Luo L, et al. AAPS J. 2007 Oct 5;9(3):E329-35.
3. Zhu S, et al. Eur J Pharm Sci. 2009 Jul 12;37(5):573-80.
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