Polθ degrader 1

Chemical Structure : Polθ degrader 1

Catalog No.: PC-26688Not For Human Use, Lab Use Only.

Polθ degrader 1 is a potent efficient degrader of DNA polymerase theta (Polθ).

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Biological Activity

Polθ degrader 1 is a potent efficient degrader of DNA polymerase theta (Polθ).

M.Wt	754.26
Formula	C37H36ClN9O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2'-chloro-N-(5-((5-(1-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-4-yl)pyridin-2-yl)methoxy)-1,3,4-thiadiazol-2-yl)-5'-methoxy-6-methyl-[4,4'-bipyridine]-3-carboxamide

1. Patent WO2024149349 A1.