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Pranlukast

Chemical Structure : Pranlukast

CAS No.: 103177-37-3

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Pranlukast (ONO-1078, ONO1078, SB 205312)

Catalog No.: PC-23321Not For Human Use, Lab Use Only.

Pranlukast (SB 205312, ONO-1078) is a highly potent, selective and competitive leukotriene antagonist, inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Ki values of 0.63 nM, 0.99 nM, and 5640 nM, respectively.

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50 mg $58 In stock
100 mg $88 In stock
250 mg $128 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pranlukast (SB 205312, ONO-1078) is a highly potent, selective and competitive leukotriene antagonist (CysLT1 receptor), inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Ki values of 0.63 nM, 0.99 nM, and 5640 nM, respectively.

Physicochemical Properties

M.Wt 481.51
Formula C27H23N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl)-4-(4-phenylbutoxy)benzamide

References

1. Torii T, et al. Heart Vessels. 1988;4(2):104-11.

2. Fujiwara H, et al. Prostaglandins Leukot Essent Fatty Acids. 1993 Mar;48(3):241-6.

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