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Chemical Structure : Presatovir
CAS No.: 1353625-73-6
Catalog No.: PC-45063Not For Human Use, Lab Use Only.
Presatovir (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor with mean EC50 of 0.43 nM against a panel of 75 RSV A and B clinical isolates.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $398 | In stock | |
| 25 mg | $658 | In stock | |
| 100 mg | $1480 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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Presatovir (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor with mean EC50 of 0.43 nM against a panel of 75 RSV A and B clinical isolates.
Presatovir (GS-5806) exhibits low cytotoxicity in human cell lines and primary cell cultures (selectivity > 23,000-fold).
Presatovir (GS-5806) shows excellent antiviral efficacy in the cotton rat model of RSV infection.
| M.Wt | 532.0581 | |
| Formula | C24H30ClN7O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Methanesulfonamide, N-[2-[[(2S)-2-[5-[(3S)-3-amino-1-pyrrolidinyl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]-1-piperidinyl]carbonyl]-4-chlorophenyl]- |
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1. Mackman RL, et al. J Med Chem. 2015 Feb 26;58(4):1630-43.
2. Jordan R, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4889-900.
3. Perron M, et al. Antimicrob Agents Chemother. 2015 Dec 14;60(3):1264-73.
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