Chemical Structure : Pridopidine
CAS No.: 346688-38-8
Catalog No.: PC-63432Not For Human Use, Lab Use Only.
Pridopidine (ACR16, FR-310826, ASP-2314, Huntexil) is a selective and potent Sigma-1 receptor agonist.
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Pridopidine (ACR16, FR-310826, ASP-2314, Huntexil) is a selective and potent Sigma-1 receptor agonist.
Pridopidine also is a specific dopamine stabilizer without no partial agonism; shows robust dose-dependent striatal D2 occupancy with ED50 of 18.99 mg/kg s.c. in vivo, shows high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in rats.
M.Wt | 281.414 | |
Formula | C15H23NO2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-(3-(methylsulfonyl)phenyl)-1-propylpiperidin |
1. Natesan S, et al. J Pharmacol Exp Ther. 2006 Aug;318(2):810-8.
2. Nilsson M, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Jul;28(4):677-85.
3. Seeman P, et al. Synapse. 2009 Oct;63(10):930-4.
4. Pettersson F, et al. J Med Chem. 2010 Mar 25;53(6):2510-20.
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