ProTx II | NaV1.7 inhibitor | Probechem Biochemicals

Chemical Structure : ProTx II

CAS No.: 484598-36-9

Catalog No.: PC-72206Not For Human Use, Lab Use Only.

ProTx II (Protoxin II) is a selective NaV1.7 channel blocker with IC50 of 0.3 nM, 100-fold selectivity over other sodium channel subtypes.

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Biological Activity

ProTx II (Protoxin II) is a selective NaV1.7 channel blocker with IC50 of 0.3 nM, 100-fold selectivity over other sodium channel subtypes.

M.Wt	3828
Formula	C168H250N46O41S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility
Chemical Name/SMILES	Tyr-Cys2-Gln-Lys-Trp-Met-Trp-Thr-Cys9-Asp-Ser-Glu-Arg-Lys-Cys15-Cys16-Glu-Gly-Met-Val-Cys21-Arg-Leu-Trp-Cys25-Lys-Lys-Lys-Leu-Trp-OH, Cys2-Cys16, Cys9-Cys21 and Cys15-Cys25

1. Xu H, et al. Cell. 2019 Feb 7;176(4):702-715.e14.