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Pyrazofurin

Chemical Structure : Pyrazofurin

CAS No.: 30868-30-5

Pyrazofurin (Pyrazomycin, NSC 143095)

Catalog No.: PC-20259Not For Human Use, Lab Use Only.

Pyrazofurin (Pyrazomycin, NSC 143095) is a nucleoside analog that potently inhibits orotidine 5'-monophosphate (OMP) decarboxylase, thereby interfering with de novo synthesis of uridine nucleotides and resulting in cytotoxicity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pyrazofurin (Pyrazomycin, NSC 143095) is a nucleoside analog that potently inhibits orotidine 5'-monophosphate (OMP) decarboxylase, thereby interfering with de novo synthesis of uridine nucleotides and resulting in cytotoxicity.

Physicochemical Properties

M.Wt 259.22
Formula C9H13N3O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Pyrazole-3-carboxamide, 4-hydroxy-5-β-D-ribofuranosyl-

References

1. Ringer DP, et al. 1991 Spring;6(1):19-27.
2. Peters GJ, et al. Nucleosides Nucleotides Nucleic Acids. 2018;37(6):329-339.

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