Chemical Structure : Q308
CAS No.: 2700216-93-7
Catalog No.: PC-38556Not For Human Use, Lab Use Only.
Q308 is a small molecule that silences the latent HIV-1 provirus by inhibiting Tat-mediated gene transcription and selectively downregulates the expression levels of the facilitated chromatin transcription (FACT) complex.
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Q308 is a small molecule that silences the latent HIV-1 provirus by inhibiting Tat-mediated gene transcription and selectively downregulates the expression levels of the facilitated chromatin transcription (FACT) complex.
Q308 induced the preferential apoptosis in HIV-1 latently infected cells, Q308 may reduce the size of the viral reservoir.
M.Wt | 301.302 | |
Formula | C15H15N3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
6,7,8-trimethoxy-2-(1H-pyrrol-2-yl)quinazolin-4(3H)-one |
1. Zhou CL, et al. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0047021.
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