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QD 232

Chemical Structure : QD 232

CAS No.: 1527467-32-8

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QD 232 (QD232)

Catalog No.: PC-62576Not For Human Use, Lab Use Only.

QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation, decreasing pancreatic cancer cell viability and migration.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation, decreasing pancreatic cancer cell viability and migration.
    QD 232 arrests cell cycle progression and induces apoptosis at low micromolar concentrations, shows effectivity in drug-resistant cancer cell lines.

    Physicochemical Properties

    M.Wt 293.282
    Formula C16H11N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-((3-acetylphenyl)amino)quinazoline-5,8-dione

    References

    1. Pathania D, et al. Br J Pharmacol. 2015 Jan;172(1):50-63.

    2. Kuang Y, et al. J Med Chem. 2018 Feb 22;61(4):1576-1594.

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