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Chemical Structure : QGC583
Catalog No.: PC-23036Not For Human Use, Lab Use Only.
QGC583 is a potent, selective aminopeptidase A (APA) with IC50 of 4 nM, >5000-fold selective over aminopeptidase N (APN).
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QGC583 is a potent, selective aminopeptidase A (APA) with IC50 of 4 nM, >5000-fold selective over aminopeptidase N (APN).
QGC583 penetrates the brain and reach brain APA after i.v. administration in rats, but also strongly inhibits renal and cardiac APA activities.
| M.Wt | 271.25 | |
| Formula | C12H18NO4P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Balavoine F, et al. Bioorg Med Chem Lett. 2024 Sep 2:129940.
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