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Qstatin

Chemical Structure : Qstatin

CAS No.: 902688-24-8

Qstatin

Catalog No.: PC-35527Not For Human Use, Lab Use Only.

Qstatin is a potent SmcR inhibitor in V. vulnificus. with IC50 of 208.9 nM, shows pan-QS (quorum sensing) inhibitor activity in diverse Vibrio species.

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Biological Activity

Qstatin is a potent SmcR inhibitor in V. vulnificus. with IC50 of 208.9 nM, shows pan-QS (quorum sensing) inhibitor activity in diverse Vibrio species.
Qstatin binds tightly to a putative ligand-binding pocket on SmcR, the LuxR homologue in V. vulnificus, and affects expression of QS-regulated genes.

Physicochemical Properties

M.Wt 293.153
Formula C7H5BrN2O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(5-bromothiophene-2-sulfonyl)-1H-pyrazole

References

1. Kim BS, et al. MBio. 2018 Jan 30;9(1). pii: e02262-17.

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