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Quinobene

Chemical Structure : Quinobene

CAS No.: 140942-13-8

Quinobene

Catalog No.: PC-61258Not For Human Use, Lab Use Only.

Quinobene is a HIV-1 surface-membrane inhibitor, also is a Fap1-blocking small molecule that replicates SLV peptied functions.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Quinobene is a HIV-1 surface-membrane inhibitor, also is a Fap1-blocking small molecule that replicates SLV peptied functions.
    Quinobene blocks co-immunoprecipitation of Fas or Apc with Fap1, decreases β-catenin and survivin in Bcr-abl+ murine bone marrow cells.
    Quinobene does not alter Fap1-independent Bcr-abl targets, impairs Bcr-abl+ cell outgrowth.

    Physicochemical Properties

    M.Wt 930.723
    Formula C32H18N6Na4O14S4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (7E)-8-oxo-7-[[4-[(Z)-2-[4-[(2E)-2-(8-oxo-5-sulfonatoquinolin-7-ylidene)hydrazinyl]-2-sulfonatophenyl]ethenyl]-3-sulfonatophenyl]hydrazinylidene]quinoline-5-sulfonate tetrasodium

    References

    1. Gruszecka-Kowalik E, et al. Biochem Biophys Res Commun. 1992 Sep 30;187(3):1409-17.

    2. Tobin GJ, et al. Antiviral Res. 1996 Dec;33(1):21-31.

    3. Huang W, et al. Leukemia. 2016 Jul;30(7):1502-9.

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