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Chemical Structure : R1-ICR-5
Catalog No.: PC-22429Not For Human Use, Lab Use Only.
R1-ICR-5 is a selective and potent RIPK1 PROTAC degrader, triggers VHL-mediated degradation of RIPK1, deregulates TNFR1 and TLR3 signaling, enhances innate immune signaling and necroptosis
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R1-ICR-5 is a selective and potent RIPK1 PROTAC degrader, triggers VHL-mediated degradation of RIPK1, deregulates TNFR1 and TLR3 signaling, enhances innate immune signaling and necroptosis
| M.Wt | 1007.32 | |
| Formula | C54H70N8O7S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Mannion J, et al. Immunity. 2024 May 15:S1074-7613(24)00230-9.
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