Chemical Structure : R805
CAS No.: 457940-87-3
Catalog No.: PC-20490Not For Human Use, Lab Use Only.
R805 is a small molecule modulator of gp130 receptor pro-inflammatory signaling, targets a signaling tyrosine 814 (Y814) within gp130, modulates gp130 Y814 upstream of the SRC and MAPK circuit, elicits a protective effect on tissues after injury.
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R805 is a small molecule modulator of gp130 receptor pro-inflammatory signaling, targets a signaling tyrosine 814 (Y814) within gp130, modulates gp130 Y814 upstream of the SRC and MAPK circuit, elicits a protective effect on tissues after injury.
M.Wt | 295.36 | |
Formula | C16H13N3OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
O=C(NC1=NC(C2=CC=C(C)C=C2)=CS1)C3=NC=CC=C3 |
1. Ruzanna Shkhyan, et al. Sci Transl Med. 2023 Mar 22;15(688):eabq2395.
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