R805 | gp130 modulator | Probechem Biochemicals

Chemical Structure : R805

CAS No.: 457940-87-3

R805 (R 805)

Catalog No.: PC-20490Not For Human Use, Lab Use Only.

R805 is a small molecule modulator of gp130 receptor pro-inflammatory signaling, targets a signaling tyrosine 814 (Y814) within gp130, modulates gp130 Y814 upstream of the SRC and MAPK circuit, elicits a protective effect on tissues after injury.

Packing	Price	Stock
5 mg	$258	In stock
10 mg	$398	In stock
25 mg	$598	In stock
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Biological Activity

R805 is a small molecule modulator of gp130 receptor pro-inflammatory signaling, targets a signaling tyrosine 814 (Y814) within gp130, modulates gp130 Y814 upstream of the SRC and MAPK circuit, elicits a protective effect on tissues after injury.

Physicochemical Properties

M.Wt	295.36
Formula	C16H13N3OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(p-tolyl)thiazol-2-yl)picolinamide

References

1. Ruzanna Shkhyan, et al. Sci Transl Med. 2023 Mar 22;15(688):eabq2395.

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R805 (R 805)

Biological Activity

Physicochemical Properties

References

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