Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Tyrosine Kinase-TAM Receptor (Tyro3-Axl-Mer)-R916562
R916562

Chemical Structure : R916562

CAS No.: 1037798-41-6

Add to Favorites

R916562 (R 916562;R-916562;R562)

Catalog No.: PC-35348Not For Human Use, Lab Use Only.

R916562 (R562) is a potent, dual Axl/VEGFR2 inhibitor with celluar IC50 of 136 nM for Axl.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    R916562 (R562) is a potent, dual Axl/VEGFR2 inhibitor with celluar IC50 of 136 nM for Axl.
    R916562 blocks growth of MDA-MB-231 breast carcinomas implanted subcutaneously in nu/nu mice.
    R916562 also shows efficacy in the Caki-1 human renal carcinoma xenograft model.

    Physicochemical Properties

    M.Wt 536.099
    Formula C26H30ClN9S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1H-1,2,4-Triazole-3,5-diamine, N3-[4-[4-(1R,2R,4S)-bicyclo[2.2.1]hept-2-yl-1-piperazinyl]phenyl]-1-(2-chloro-7-methylthieno[3,2-d]pyrimidin-4-yl)-

    References

    1. Goff D, et al. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3766-3771.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: