Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : R916562
Catalog No.: PC-35348Not For Human Use, Lab Use Only.
R916562 (R562) is a potent, dual Axl/VEGFR2 inhibitor with celluar IC50 of 136 nM for Axl.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
R916562 (R562) is a potent, dual Axl/VEGFR2 inhibitor with celluar IC50 of 136 nM for Axl.
R916562 blocks growth of MDA-MB-231 breast carcinomas implanted subcutaneously in nu/nu mice.
R916562 also shows efficacy in the Caki-1 human renal carcinoma xenograft model.
| M.Wt | 536.099 | |
| Formula | C26H30ClN9S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Goff D, et al. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3766-3771.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
