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Chemical Structure : RB-005
Catalog No.: PC-35529Not For Human Use, Lab Use Only.
RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2.
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RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2.
| M.Wt | 317.517 | |
| Formula | C21H35NO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Baek DJ, et al. Chem Commun (Camb). 2013 Mar 14;49(21):2136-8.
2. Baek DJ, et al. J Med Chem. 2013 Nov 27;56(22):9310-27.
3. MacRitchie N, et al. Cell Signal. 2016 Aug;28(8):946-55.
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