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RB-005

Chemical Structure : RB-005

CAS No.: 1425049-20-2

RB-005 (RB005)

Catalog No.: PC-35529Not For Human Use, Lab Use Only.

RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2.

    Physicochemical Properties

    M.Wt 317.517
    Formula C21H35NO
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(4-octylphenethyl)piperidin-4-ol

    References

    1. Baek DJ, et al. Chem Commun (Camb). 2013 Mar 14;49(21):2136-8.

    2. Baek DJ, et al. J Med Chem. 2013 Nov 27;56(22):9310-27.

    3. MacRitchie N, et al. Cell Signal. 2016 Aug;28(8):946-55.

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