RDS-04-010

Chemical Structure : RDS-04-010

Catalog No.: PC-24696Not For Human Use, Lab Use Only.

RDS-04-010 is a novel atypical dopamine transporter (DAT) inhibitor with Ki of 245 nM (rDAT), binds to an inward-facing conformation of DAT.

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Biological Activity

RDS-04-010 is a novel atypical dopamine transporter (DAT) inhibitor with Ki of 245 nM (rDAT), binds to an inward-facing conformation of DAT.
RDS-04-010 inhibits cocaine self-administration under FR2 reinforcement.
RDS-04-010 inhibits cocaine self-administration under PR reinforcement schedule.
RDS-03-094 upward shifts cocaine self-administration dose-response curve.

Physicochemical Properties

M.Wt	450.59
Formula	C24H32F2N2O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Piperazineethanol, 4-[2-[[bis(4-fluorophenyl)methyl]sulfinyl]ethyl]-alpha,2,6-trimethyl-, (2R,6S)-rel-

References

1. Soler-Cedeno O, et al. Transl Psychiatry. 2025 May 24;15(1):182.

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RDS-04-010

Biological Activity

Physicochemical Properties

References

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