RDS1759

Chemical Structure : RDS1759

Catalog No.: PC-24020Not For Human Use, Lab Use Only.

RDS1759 is a specific small molecule inhibitor of HIV-1 RT-associated RNase H activity with IC50 of 8.6 uM (mutated HIV-1 RT R448A), inhibits viral inhibition rate with IC50 of 0.17 uM.

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Biological Activity

RDS1759 is a specific small molecule inhibitor of HIV-1 RT-associated RNase H activity with IC50 of 8.6 uM (mutated HIV-1 RT R448A), inhibits viral inhibition rate with IC50 of 0.17 uM.

Physicochemical Properties

M.Wt	359.81
Formula	C19H18ClNO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethyl 6-[1-[(2-chlorophenyl)methyl]-1H-pyrrol-2-yl]-2,4-dioxo-5-hexenoate

References

1. Corona A, et al. Antimicrob Agents Chemother. 2014 Oct;58(10):6101-10.

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RDS1759

Biological Activity

Physicochemical Properties

References

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