Chemical Structure : RET agonist BT18
CAS No.: 924811-53-0
Catalog No.: PC-49616Not For Human Use, Lab Use Only.
RET agonist BT18 is a small molecule allosteric agonist (ligand) of GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function.
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RET agonist BT18 is a small molecule allosteric agonist (ligand) of GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function.
M.Wt | 637.65 | |
Formula | C30H31F4N3O6S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(4-(5-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-methoxyphenyl)piperazin-1-yl)(4-fluoro-2-(trifluoromethyl)phenyl)methanone |
1. Larisa Ivanova, et al. ACS Omega. 2018 Sep 30;3(9):11407-11414.
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