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RET agonist BT18

Chemical Structure : RET agonist BT18

CAS No.: 924811-53-0

RET agonist BT18 (BT18)

Catalog No.: PC-49616Not For Human Use, Lab Use Only.

RET agonist BT18 is a small molecule allosteric agonist (ligand) of GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RET agonist BT18 is a small molecule allosteric agonist (ligand) of GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function.

Physicochemical Properties

M.Wt 637.65
Formula C30H31F4N3O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4-(5-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-methoxyphenyl)piperazin-1-yl)(4-fluoro-2-(trifluoromethyl)phenyl)methanone

References

1. Larisa Ivanova, et al. ACS Omega. 2018 Sep 30;3(9):11407-11414.

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